# Boolean network model of the control of the fission yeast cell cycle regulation from # "Boolean Network Model Predicts Cell Cycle Sequence of Fission Yeast", # M. I. Davidich, S. Bornholdt, PLoS ONE. 2008 Feb 27, 3(2):e1672. #total number of nodes .v 10 # labels of nodes and names of corresponding components # 1 = Start # 2 = SK # 3 = Ste9 # 4 = Cdc2/Cdc13 # 5 = Rum1 # 6 = PP # 7 = Cdc25 # 8 = Slp1 # 9 = Wee1/Mik1 # 10 = Cdc2/Cdc13* # # The threshold is -1 for the node Cdc2/Cdc13 and 1 for Cdc2/Cdc13* # for all other nodes the threshold is 0 # As a result of simulation, we get the following 13 attractors of length 1: # 0010100010 # 0010001000 # 0010101010 # 0010100000 # 0010000000 # 0000100000 # 0010101000 # 0000100010 # 0001001000 # 0000101000 # 0010000010 # 0010001010 # 0000101010 # 1 = Start .n 1 0 # 2 = SK .n 2 1 1 1 1 0 0 # 3 = Ste9 .n 3 5 2 3 4 6 10 010-0 1 -1010 1 01-10 1 0101- 1 0-010 1 10--- 0 1-1-- 0 -01-- 0 1--0- 0 -0-0- 0 --10- 0 1---1 0 -0--1 0 --1-1 0 ---01 0 # 4 = Cdc2/Cdc13 .n 4 4 3 4 5 8 -100 1 01-0 1 010- 1 0-00 1 10-- 0 1-1- 0 -01- 0 1--1 0 -0-1 0 --11 0 # 5 = Rum1 .n 5 5 2 4 5 6 10 -0111 1 001-0 1 0-110 1 00-10 1 -10-- 0 -1-0- 0 --00- 0 1---0 0 -1--1 0 --0-1 0 ---01 0 # 6 = PP .n 6 1 8 1 1 0 0 # 7 = Cdc25 .n 7 3 4 6 7 -01 1 1-1 1 10- 1 01- 0 0-0 0 -10 0 # 8 = Slp1 .n 8 1 10 1 1 0 0 # 9 = Wee1/Mik1 .n 9 3 4 6 9 0-1 1 -11 1 01- 1 10- 0 1-0 0 -00 0 # 10 = Cdc2/Cdc13* .n 10 6 3 5 7 8 9 10 001001 1 1----- 0 -1---- 0 --0--- 0 ---1-- 0 ----1- 0 -----0 0