# Boolean network model of the control of the mammalian cell cycle from # "Dynamical Analysis of a Generic Boolean Model for the Control of the # Mammalian Cell Cycle", A. Faure, A. Naldi, C. Chaouiya, D. Thieffry, # Bioinformatics, 2006, vol. 22, no. 14, pp. e124-e131. #total number of nodes .v 10 # labels of nodes and names of corresponding components # 1 = CycD # 2 = CycE # 3 = Rb # 4 = E2F # 5 = CycA # 6 = p27 # 7 = Cdc20 # 8 = UbcH10 # 9 = Cdh1 # 10 = CycB # As a result of simulation, we get the following 2 attractors: # # 1101100010 # 1100100000 # 1000100101 # 1000101101 # 1000001110 # 1001000110 # 1101000010 # Attractor 1 is of length 7 # # 0010010010 # Attractor 2 is of length 1 # 1 = CycD .n 1 1 1 1 1 0 0 # 2 = CycE .n 2 2 3 4 01 1 1- 0 -0 0 # 3 = Rb .n 3 5 1 2 5 6 10 000-0 1 0--10 1 -1-0- 0 --10- 0 1---- 0 ----1 0 # 4 = E2F .n 4 4 3 5 6 10 0-10 1 00-0 1 -10- 0 1--- 0 ---1 0 # 5 = CycA .n 5 6 3 4 5 7 8 9 0-10-0 1 01-0-0 1 0-100- 1 01-00- 1 -00--- 0 ----11 0 1----- 0 ---1-- 0 # 6 = p27 .n 6 5 1 2 5 6 10 0-010 1 00-10 1 000-0 1 -11-- 0 -1-0- 0 --10- 0 1---- 0 ----1 0 # 7 = Cdc20 .n 7 1 10 1 1 0 0 # 8 = UbcH10 .n 8 5 5 7 8 9 10 --1-1 1 -11-- 1 1-1-- 1 ---0- 1 --01- 0 00-10 0 # 9 = Cdh1 .n 9 4 5 6 7 10 -1-0 1 0--0 1 --1- 1 --01 0 100- 0 # 10 = CycB .n 10 2 7 9 00 1 1- 0 -1 0